在爱尔兰长度老龄化研究中,老年人群中的体力活动剂量和抑郁症
Eamon Laird1,2,3, Charlotte Lund Rasmussen1,3,4, Rose Anne Kenny1,2,3
1Physical Activity for Health Research Centre, Health Research Institute, University of Limerick, Limerick, Ireland.
JAMA network open
|July 10, 2023
概括
定期进行中度至剧烈的体力活动 (MVPA) 能显著保护老年人免受抑郁症的侵害. 即使是较低剂量的MVPA也提供抗抑郁药的益处,更高的活性水平产生更大的风险降低.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 抑郁症是老年人严重的健康问题,与身体,社会和认知能力的下降有关.
- 定期进行中度至剧烈的体力活动 (MVPA) 与抑郁症风险降低有关,但最佳剂量尚不清楚.
研究的目的:
- 调查不同剂量的MVPA与老年人抑郁症状或严重抑郁症之间的关系.
- 为了确定慢性疾病状态是否会影响MVPA对抑郁症的保护作用.
主要方法:
- 来自爱尔兰老龄化纵向研究 (TILDA) 的4016名老年人的长度队列研究,持续了10年.
- 使用国际体力活动问卷评估MVPA,并将其分类为不同的剂量水平 (每周MET分钟).
- 抑郁症症状和严重抑郁症使用验证的天平和诊断访谈进行测量;使用多变量回归模型分析数据.
主要成果:
- 与没有活动相比,每周400-600MET分钟的MVPA剂量与抑郁症状率降低16%,抑郁的几率降低43%.
- 患有慢性疾病的老年人需要600-1200MET分钟/周进行类似的保护,而没有慢性疾病的老年人需要超过2400MET分钟/周.
- 更高的MVPA剂量与更大的抑郁风险降低相关 (更大的AIRR降低).
结论:
- 在低于当前老年人一般健康建议的MVPA剂量下观察到显著的抗抑郁药益处.
- 公共卫生倡议应该探索较低的身体活动值在老年人群中预防抑郁症的可行性,考虑到慢性疾病状态.
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