在 laparoscopic 手术中对前额脑电图波形和相振幅合的感知效应
Tzu Chun Wang1,2, Wei Yi Li2, Jerry Cheng-Yen Lai3,4
1From the Department of Anaesthesia, Taitung MacKay Memorial Hospital, Taitung, Taiwan.
Anesthesia and analgesia
|July 10, 2023
概括
脑电图 (EEG) 的α功率在腹腔镜外科手术中有害刺激期间下降. 德尔塔-α合也会减少,这表明在麻醉期间监测 nociception-analgesia平衡的潜在新标志物.
科学领域:
- 麻醉学 麻醉学
- 神经科学是一个神经科学.
- 信号处理 信号处理
背景情况:
- 在麻醉期间的脑电图 (EEG) 图案反映了 nociception-analgesia 平衡.
- 虽然已知对有害刺激的反应是α脱落和delta/beta兴奋,但对其他EEG信号的理解较少.
- 研究各种EEG信号可以揭示新的感觉标记物,并加深我们对疼痛神经生理学的理解.
研究的目的:
- 分析腹腔镜手术期间脑电图 (EEG) 频率模式和相振幅合的变化.
- 为了确定与 nociception 和麻醉下的止痛平衡相关的新型EEG标志物.
主要方法:
- 评估了34名接受腹腔镜手术的患者.
- 分析了EEG频段功率和相振幅在切口,吸气和阿片类药物阶段的合.
- 使用重复测量ANOVA与混合模型和邦费罗尼校正进行统计分析.
主要成果:
- 观察到切割后和吸气期间的α功率百分比显著下降,在阿片类药物管理后恢复.
- 在切口后和 insufflation 期间发现delta-alpha相幅合的调制指数 (MI) 降低,这也在阿片类药物后恢复.
- 这些变化突出了在手术期间对有害刺激的反应中特定的EEG签名变化.
结论:
- 在有害刺激期间的α脱落在sevoflurane麻醉下的腹腔镜手术中得到证实.
- 在有害刺激期间降低的三角α相振幅合 (MI) 表明其作为一种新型指标的潜力.
- 脑电图的相振幅合分析提供了一种有前途的新方法,用于评估麻醉中的感觉-疼痛平衡.
相关概念视频
Local Anesthetics: Differential Sensitivity of Nerve Fibers
873
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
873
Local Anesthetics: Adverse Effects
455
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
455


