目前治疗肝细胞癌的现有疗法
Kelley Coffman-D'Annibale1, Changqing Xie1, Donna M Hrones1
1National Cancer Institute, Gastrointestinal Malignancies Section, Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, Bethesda, MD, USA.
Carcinogenesis
|July 10, 2023
概括
肝细胞癌 (HCC) 是全球癌症死亡的主要原因,特别是在发展中国家. 本综述涵盖了目前对HCC的治疗方法,从早期到晚期,包括新的全身疗法.
科学领域:
- 在瘤学瘤学.
- 肝病学 肝病学是一种肝病学.
背景情况:
- 初级肝癌,主要是肝细胞癌 (HCC),是全球癌症相关死亡的第三大原因.
- 在患有慢性肝病的患者中,HCC经常出现,包括病毒性肝炎,非酒精性脂肪肝炎 (NASH) 和肝硬化.
- 预后受瘤特征,肝功能和性能状况的影响,巴塞罗那诊所肝癌 (BCLC) 阶段系统提供预后分层.
结论:
- 瘤癌的管理正在不断发展,针对瘤生物学和微观环境的全身疗法取得了显著进展.
- 对现有治疗方法的全面了解,从局部疗法到全身药物,对于优化患者的治疗结果至关重要.
- 未来的方向涉及进一步改进基于分子见解和临床试验数据的治疗策略.
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