耳间频率不匹配联合调节神经大脑干双耳交互和行为耳间时差灵敏度在人类
Carol A Sammeth1, Andrew D Brown2, Nathaniel T Greene3
1Department of Physiology and Biophysics, University of Colorado School of Medicine, RC1-N: Rm 7106, 12800 E. 19th Avenue, Aurora, CO 80045, USA.
Hearing research
|July 10, 2023
概括
声间频率不匹配会影响听觉脑干反应的双耳交互组件 (BIC),并降低对声间时差 (ITD) 线索的行为敏感性. 这些发现表明,BIC可能检测到影响声音定位的光谱不匹配.
科学领域:
- 听觉神经科学 听觉神经科学
- 精神声学是一种精神声学.
- 生物标志物 生物标志物
背景情况:
- 听觉脑干反应 (ABR) 的双耳交互组件 (BIC) 测量双耳处理.
- 听觉输入的光谱不匹配可以损害双耳听力,特别是间声时间差 (ITD) 灵敏度.
- BIC作为检测这种光谱不匹配的生物标志物的潜力令人感兴趣.
研究的目的:
- 调查声间频率不匹配 (IFM) 对BIC的影响.
- 评估IFM如何影响人类的行为ITD敏感性.
- 探索BIC,ITD感知和IFM之间的关系.
主要方法:
- 记录了双耳和单耳ABR,以响应不同IFM的窄带音调.
- 来自ABR的计算BIC.
- 使用同样的刺激的心理物理横向化任务测量了ITD歧视值.
- 分析了IFM和声音水平对BIC和ITD值的影响.
主要成果:
- 与频率匹配条件相比,IFM显著降低了BIC振幅.
- 行为性ITD歧视门在IFM上升,特别是在较低的音量水平上.
- IFM对ITD值的影响在较低的噪音水平时更为明显.
- 经验测量BIC和模型预测与融合和横向声音的感知边界保持一致.
结论:
- BIC对耳间频率不匹配非常敏感.
- IFM降低了ITD的灵敏度,特别是在较低的音量水平.
- BIC可以作为生物标志物来检测影响双耳听力和声音定位的光谱不匹配.
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