使用圆束计算断层扫描评估宫性 dystonia 中的轴旋转运动
Jean-Pierre Bleton1, Raphaël Portero2, Kévin Zuber2
1Neurology Department, Hôpital Fondation Adolphe de Rothschild, Paris, France; Clinical Research Department, Hôpital Fondation Adolphe de Rothschild, Paris, France.
Clinical biomechanics (Bristol, Avon)
|July 10, 2023
概括
宫性 dystonia 显著改变头部姿势,并减少宫脊椎的旋转,特别是在脊椎上部和大西洋轴关节. 治疗策略应该考虑对这些特定的宫区域的影响.
科学领域:
- 神经学 神经学
- 生物力学 生物力学
- 医疗成像医学成像
背景情况:
- 宫性 dystonia 导致 involuntary 部肌肉收缩和异常的头部姿势.
- 肉毒神经毒素注射是主要的治疗方法,辅助成像分类 (COL-CAP) 识别受影响的宫段.
- 了解 dystonia 对椎的姿势和旋转的影响对于有效治疗至关重要.
研究的目的:
- 为了研究宫性 dystonia 对宫脊椎姿势和横平面的旋转运动的影响.
- 为了比较宫脊椎动力学与宫脊椎 dystonia 和健康对照的个体之间.
主要方法:
- 一项比较研究涉及10名患有宫性 dystonia 和10匹匹配的健康对照.
- 三维 (3D) 姿势和部运动范围在轴旋转中被使用形光束CT (CBCT) 捕获.
- 测量集中在椎上部,从骨到第四椎.
主要成果:
- 与健康受试者相比,患有宫性 dystonia 的人与中性头部姿势的偏差显著增加 (p=0.007).
- 在整个椎脊柱 (p=0.026) 和椎脊柱上部 (p=0.004) 中观察到明显减少的旋转运动范围.
- 形光束CT显示,宫性迪斯托尼的运动失调主要影响上椎,特别是大西洋轴关节.
结论:
- 宫性 dystonia 扰乱正常的运动模式,影响上部宫脊椎和大西洋轴关节.
- 宫 dystonia 的治疗方法应该更彻底地考虑宫上部旋转肌肉的参与.
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