相关实验视频
Updated: Jul 24, 2025
08:40
Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
20.1K
在美国NICU的尿路感染流行病学
Ryan Kilpatrick1,2, Angelique E Boutzoukas1,2, Elizabeth Chan2
1Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
American journal of perinatology
|July 10, 2023
概括
尿路感染 (UTI) 在出生时体重非常低 (VLBW) 的婴儿中很常见,特别是男性和那些住院时间较长的婴儿. 建议在怀疑VLBW新生儿晚发性败血症时进行早期尿液培养.
科学领域:
- 新生儿传染病 新生儿传染病
- 儿童传染病 儿童传染病
- 临床微生物学 临床微生物学
背景情况:
- 尿路感染 (UTI) 是新生儿重症监护病房的重要发病原因之一.
- 非常低出生体重 (VLBW) 的婴儿 (<1,500g) 特别容易感染感染,包括尿路感染.
- 了解VLBW婴儿的尿路感染流行病学对于有效的管理和预防至关重要.
研究的目的:
- 调查VLBW婴儿中尿路感染的发病率和临床特征.
- 为了确定与该人群中尿路感染发展相关的风险因素.
- 确定常见的病原体和一致的阳性血液培养率VLBW婴儿的尿路感染.
主要方法:
- 一项多中心观察队列研究包括从2010年到2018年住院的VLBW婴儿 (妊娠年龄 ≤32周).
- 收集了人口统计和临床数据,并比较了患有和没有尿路感染的婴儿.
- 使用多变量逻辑回归来确定与尿路感染诊断相关的因素.
主要成果:
- 这项研究分析了86,492名婴儿,其中5,988名 (7%) 被诊断为尿路感染.
- 常见的病原体包括 *Enterococcus* spp. (20%),大肠杆菌 (19%) 和克莱布西埃拉 (Klebsiella) 菌种. 这一比例为18% (18%). * 坎迪达 * spp. 的种类. 占非细菌性感染的6%.
- 尿路感染与更低的妊娠年龄,男性性别,阴道分娩,产前类固醇暴露和更长的住院时间有关.
结论:
- 尿路感染是VLBW婴儿中普遍存在的感染,发病率因人口子组而异.
- 这些发现强调了考虑VLBW婴儿晚发性败血症尿液培养的重要性.
- 对VLBW婴儿的尿路感染预防策略的进一步研究是有必要的.
相关概念视频
01:25Urinary Tract Infection II: Pathophysiology
19
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
19
01:26Urinary Tract Infection I: Introduction
26
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
26
01:17Urinary Tract Infection IV: Nursing Management
26
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
26
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
15
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
15
01:27Acute Pyelonephritis I: Introduction
23
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
23
01:26Urine Studies II: Urine Culture and Sensitivity Test
58
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
58