第二眼参与近视性黄斑性新血管化的发生率和危险因素
Monica Ravenstijn1, Caroline C W Klaver2, Suzanne Yzer3
1Rotterdam Ophthalmic Institute, Rotterdam Eye Hospital, Rotterdam, the Netherlands; Department Of Ophthalmology, Erasmus Medical Center, Rotterdam, the Netherlands.
Ophthalmology. Retina
|July 10, 2023
概括
高近视患者有很大的风险在第二眼中发展近视性黄斑新血管化 (MNV). 年轻的患者 (<40岁) 面临更高的风险,需要密切监测.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 近视研究 近视研究
背景情况:
- 高近视是导致视力障碍的主要原因.
- 近视性黄斑新血管化 (MNV) 可以影响一只或两只眼睛,导致视力丧失.
- 了解第二眼病的风险因素和发病率对于患者管理至关重要.
研究的目的:
- 为了确定第二眼近视MNV的累积发病率.
- 为了确定与高近视患者的眼睛参与相关的风险因素.
- 为单边近视MNV患者的临床监测策略提供信息.
主要方法:
- 对88名高近视患者 (欧洲族裔) 的纵向数据进行了回顾性分析,这些患者在一只眼睛被诊断出MNV.
- 收集的数据包括球形等价,轴长,以及底缩或漆裂纹的存在.
- 考克斯的比例危险模型被用来分析第二眼参与的风险因素.
主要成果:
- 第二眼近视性MNV的累积发病率在2年后为8%,5年后为21%,10年后为38%.
- 最初呈现时年龄小于40岁的患者,双边MNV的风险高3.8倍.
- 漆裂显示出风险增加的趋势,但没有达到统计学意义.
结论:
- 在欧洲高近视患者中,第二眼近视MNV的发病率与亚洲人群相似.
- 年龄较小 (<40岁) 是双边近视性MNV的重要风险因素.
- 临床医生应该保持高度的意识和密切监测第二眼的参与,特别是在年轻的患者.
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