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Updated: Jul 24, 2025

Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation
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Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation

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在LTP期间对Ca2+透AMPA受体的功能表达的时间和定量分析

Yoshihiko Wakazono1, Ryosuke Midorikawa2, Kogo Takamiya1

  • 1Department of Neuroscience, Faculty of Medicine, University of Miyazaki, Japan; Laboratory of Biophysical Research, Frontier Science Research Center, University of Miyazaki, Japan.

Neuroscience research
|July 10, 2023
PubMed
概括

透性 (CP) α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic酸受体 (AMPARs) 对于早期维持长期强化 (LTP) 是至关重要的. 在LTP期间,它们的功能表达随着时间的推移而增加.

关键词:
长期强化 (LTP) Ca(2+) 透AMPA受体 (CP-AMPAR) NASPM海马CA1神经元全细胞电压记录

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相关概念视频

Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
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