不同种族背景的双边乳房切除率的趋势:国家癌症数据库研究
Kyra Nicholson1, Kristine Kuchta2, Marie Fefferman1
1Department of Surgery, NorthShore University Health System, Evanston Hospital, Evanston, IL, USA; Department of Surgery, Pritzker School of Medicine at University of Chicago, Chicago, IL, USA.
American journal of surgery
|July 10, 2023
概括
2013年以后,双边乳房切除 (BM) 率在所有种族中都下降,种族群体之间的差异正在缩小. 这一趋势表明,在不同患者群体中,乳腺癌手术决策的公平性得到了改善.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 健康差异 在健康上的差异
背景情况:
- 双边乳房切除术 (BM) 率呈现普遍下降,但这些趋势的种族差异并未得到充分理解.
- 之前的研究表明,肌肉病率有所下降,这促使人们对这种趋势中潜在的种族差异进行调查.
研究的目的:
- 分析不同种族群体早期单侧乳腺癌双侧乳房切除 (BM) 率的趋势.
- 从2004年到2020年,确定影响BM率的患者和设施因素,跨种族人口统计数据.
主要方法:
- 利用国家癌症数据库 (NCDB) 来获取2004年至2020年的数据.
- 检查了AJCC0-II期单侧乳腺癌患者的BM率,将白人患者与黑人,西班牙裔和亚洲患者进行比较.
- 采用多变量后勤回归来确定在早期 (2004-2006) 和晚期 (2018-2020) 期间根据种族与BM相关的因素.
主要成果:
- 分析了超过1180万名患者;11.6%接受了BM. 肌肉损伤率增加到2013年,然后在所有种族中到2020年下降到11.3%.
- 虽然2013年后所有种族群体的肌肉病率都下降了,但种族仍然是一个重要的独立因素.
- 2020年,与白人患者 (OR1.00) 相比,黑人患者的肌肉瘤发生率 (OR0.66) 较低,西班牙裔和亚洲裔患者的患病率也有类似的减少.
结论:
- 自2013年以来,双边乳房切除 (BM) 率在所有种族中显著下降.
- 观察到的BM率的下降导致不同种族群体之间的差异缩小.
- 尽管差距越来越小,但种族仍然是一个独立的因素,影响了接受双边乳房切除术的可能性.
相关概念视频
Cancer Survival Analysis
394
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
394
Skin Cancer
4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K


