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心力衰竭引起的认知功能障碍是由通过二型氨酸受体的细胞内Ca2+泄漏介导的

Haikel Dridi1, Yang Liu2, Steven Reiken2

  • 1Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians & Surgeons, New York, NY, USA. dh2756@cumc.columbia.edu.

Nature neuroscience
|July 10, 2023
PubMed
概括

心力衰竭通过大脑中漏洞的RyR2通道引起认知功能障碍. 针对RyR2的治疗,如稳定剂或β阻塞剂,可以防止这种由心力衰竭引起的认知衰退.

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