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Updated: Jul 24, 2025

Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine
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Cxxc手指蛋白1维护肠道3组先天性淋巴细胞的恒常性和功能,与衰老有关

Xin Shen1,2,3,4, Xianzhi Gao1,3,4,5,6, Yikai Luo7,8

  • 1Institute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Nature aging
|July 10, 2023
PubMed
概括

衰老会损害免疫细胞的功能,增加感染风险. 这项研究确定了一条关键的分子途径,涉及H3K4me3修饰和Klf4在老化肠道第3组先天性淋巴细胞 (ILC3s) 中,这表明与年龄相关的感染的治疗点.

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