评估心血管疾病风险:2023年更新
Earl Goldsborough1, Erfan Tasdighi2, Michael J Blaha2
1Johns Hopkins University School of Medicine.
Current opinion in lipidology
|July 11, 2023
概括
目前用于动脉样硬化心血管疾病 (CVD) 风险评估的最佳实践强调冠状动脉 (CAC) 评分和脂蛋白[Lp[a]水平. 这些工具提高了风险分层,并指导降脂治疗决策.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 动脉样性心血管疾病 (CVD) 风险评估传统上依赖于已确定的风险因素.
- 新兴工具在识别高风险个体方面提供了更高的准确性.
- 优化风险评估对于有效的预防策略至关重要.
研究的目的:
- 审查CVD风险评估当前的最佳实践.
- 要突出辅助工具的作用,如冠状动脉 (CAC) 评分和脂蛋白[Lp]对风险分层和增强.
- 讨论新型工具的整合,例如多基因风险评分 (PRS).
主要方法:
- 关于心血管风险评估工具的最新研究的综述.
- 对冠状动脉 (CAC) 评分用于亚临床动脉样硬化检测的疗效的评估.
- 评估脂蛋白 (Lp) 和多基因风险评分 (PRS) 作为增加风险的因素.
主要成果:
- 脂蛋白[Lp[a]被确定为具有更广泛的临床应用的显著增加风险的因素.
- 冠状动脉 (CAC) 评分是评估亚临床动脉样硬化和指导降脂治疗 (LLT) 的黄金标准.
- 度和CAC评分在心脏病风险评估中提供了超越传统风险因素的实质价值.
结论:
- 在完善心血管疾病风险评估和指导LLT时,Lp(a) 和CAC评分是至关重要的.
- 未来的风险评估可能包括多基因风险评分 (PRS),以确定CAC评分的最佳时间.
- 先进的成像和PRS对个性化的预防性心脏病学策略有前途.
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