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牙周线炎和慢性疾病之间的关联:一个总体审查
Karem Paula Pinto1, Gabriella Serrão1, Cláudio Malizia Alves Ferreira1
1School of Dentistry, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.
Iranian endodontic journal
|July 11, 2023
概括
这一综合性审查评估了关于顶端牙周炎和慢性疾病的系统性审查. 它发现了中等程度的证据,将尖端牙周炎与心血管疾病和其他慢性疾病联系起来,但对糖尿病的证据有限.
科学领域:
- 口腔健康和全身疾病
- 基于证据的牙科.
- 系统审查方法论 系统审查方法论
背景情况:
- 牙周膜炎 (AP) 是一种内牙炎症性疾病,可能与各种慢性全身性疾病有关.
- 了解AP与慢性疾病相关的证据质量对于临床实践和公共卫生至关重要.
- 之前的系统审查 (SRs) 已经探索了这些关联,但它们的方法严谨性需要评估.
研究的目的:
- 批判性地评估现有系统性审查 (SRs) 的方法质量,检查牙周炎 (AP) 与慢性疾病之间的关联.
- 综合高质量的SRs关于AP与特定慢性疾病联系的证据的发现.
主要方法:
- 在七个主要科学数据库中进行了全面的系统搜索.
- 纳入标准集中在评估AP和任何慢性疾病的SR,需要有效的偏差风险评估.
- 系统审查方法,软件和工具评估2 (AMSTAR-2) 工具用于质量评估.
主要成果:
- 九项系统性审查符合纳入标准,调查了与心血管疾病,糖尿病,艾滋病毒,骨质疏松症,慢性肝病,血液疾病和自身免疫性疾病的关联.
- 包含的SR的方法质量从"低"到"高"不等.
- 在AP和心血管疾病,血液疾病,慢性肝病,骨质疏松症和自身免疫疾病之间观察到积极的关联,有适度的证据.
结论:
- 在当前关于AP和慢性疾病的SR报告中存在显著的异质性和方法问题.
- 有限的证据表明,糖尿病和AP之间存在积极的联系.
- 艾滋病毒和AP之间没有发现任何关联,而适度的证据支持AP与其他几种慢性疾病之间的联系.
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