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Targeted Cancer Therapies
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
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Treatment Resistant Cancers
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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Tumor Immunotherapy
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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Tumor Progression
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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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Cancer Therapies
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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Combination Therapies and Personalized Medicine
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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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干预瘤学:2043年及以后的未来
Mohammad Elsayed1, Stephen B Solomon1
1From the Interventional Radiology Service, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10065.
Radiology
|July 11, 2023
概括
干预性瘤学,一种微创的癌症治疗,正在成为瘤学的第四支柱. 未来的增长将受到技术和综合临床基础设施的推动.
科学领域:
- 在瘤学瘤学.
- 干预性放射学 干预性放射学
背景情况:
- 干预性瘤学是干预性放射学的一个子专业.
- 它专注于微创,图像引导的癌症治疗.
- 它被认为是瘤学的第四支柱,与医学瘤学,手术和辐射瘤学一起.
研究的目的:
- 突出干预瘤学在癌症护理中的重要作用.
- 预测该领域未来的增长机会.
- 强调新兴技术和基础设施发展的影响.
主要方法:
- 这项研究是基于当前趋势和专家预测的前性分析.
- 它综合了有关技术进步和临床整合的信息.
主要成果:
- 在精密瘤学,免疫疗法,先进成像和新型干预中存在增长的机会.
- 像人工智能,基因编辑,分子成像和机器人等新兴技术将促进这种增长.
- 完善的临床和研究基础设施对于将干预瘤学纳入标准实践至关重要.
结论:
- 干预瘤学是一个快速发展的领域,具有显著的未来潜力.
- 技术创新和强大的基础设施将决定它的演变.


