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Updated: Jul 23, 2025

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
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Clec4A4 作为一个负免疫检查点调节剂,抑制抗瘤免疫力

Tomofumi Uto1,2, Tomohiro Fukaya1,2, Shuya Mitoma1,2

  • 1Division of Immunology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Cancer immunology research
|July 11, 2023
PubMed
概括

鼠类Clec4A4 (mClec4A4) 通过损害树突细胞 (cDC) 激活来负面调节抗瘤免疫力. 通过增强抗瘤反应,阻断其人类正方形 (hCLEC4A) 对癌症免疫疗法有希望.

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