红胡卜汁摄入量的代谢生物标志物 在休息状态和运动后的摄入量
Ottavia Giampaoli1,2, Cristian Ieno3, Fabio Sciubba1,2
1NMR-Based Metabolomics Laboratory (NMLab), Sapienza University of Rome, 00185 Rome, Italy.
Nutrients
|July 11, 2023
概括
在尿液中确定了红甜菜汁 (RBJ) 摄入的生物标志物. 身体活动增强了多巴胺-3-O-硫酸盐的分泌,这表明RBJ的吸收得到了改善.
科学领域:
- 营养科学 营养科学
- 人体生理学 人体生理学
- 生物化学 生物化学
背景情况:
- 红胡卜被认为具有健康益处,但其生物活性化合物的吸收需要进一步研究.
- 了解红甜菜汁 (RBJ) 成分的肠道吸收对于最大限度地提高健康益处至关重要.
- 关于身体活动如何影响红甜菜中营养素的吸收,目前的研究有限.
研究的目的:
- 为了确定红甜菜汁 (RBJ) 摄入的尿路生物标志物.
- 为了比较RBJ微量营养素在休息状态和运动后的吸收.
- 探索身体活动对RBJ代谢产物分泌的影响.
主要方法:
- 一个三臂,单盲研究,与七名健康的志愿者.
- 参与者接受了三个会议:休息时RBJ,运动时RBJ和运动时安慰剂.
- 尿样是在摄入前和摄入后120分钟,180分钟和240分钟收集的.
主要成果:
- 确定了RBJ摄入的四个生物标志物:4-甲基二二碳酸,多巴胺-3-O-硫酸盐,谷氨酸和3 - 基酸.
- 身体活动在RBJ摄入后120分钟显著增加多巴胺-3-O-硫酸盐的分泌.
- 不同的分泌模式表明RBJ代谢产物具有不同的吸收机制.
结论:
- 尿中的多巴胺-3-O-硫酸盐与RBJ多巴胺含量相关.
- 4 - 甲基二氧化碳酸是来自RBJ的贝塔宁或贝塔胺酸的代谢产物.
- 身体活动可以通过改变的粘膜运输过程来增强RBJ吸收,从而为改善生物活性分子吸收打开道路.
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