入院血清水平与COVID-19患者的短期和长期临床结果有关
Amitai Segev1,2, Adam Sagir3,4, Shlomi Matetzky1,2
1The Leviev Cardiothoracic & Vascular Center, Chaim Sheba Medical Center, Ramat Gan 5236723, Israel.
Nutrients
|July 11, 2023
概括
血清 (sMg) 水平影响COVID-19的结果. 低和高的sMg水平都与增加的死亡率有关,但只有低的sMg在调整严重程度后,才能独立预测死亡率.
科学领域:
- 生物化学 生物化学
- 临床医学 临床医学
- 流行病学 流行病学
背景情况:
- 由于COVID-19的流行,因此需要预后标记.
- 血清 (sMg) 是一种易于获得的生物标志物.
研究的目的:
- 为了评估血清 (sMg) 水平在入院和住院COVID-19患者的临床结果之间的关联.
主要方法:
- 对1522名住院COVID-19患者的回顾性分析.
- 根据入院sMg水平,患者被分为五分之一.
- 收集和比较的人口,临床和实验室数据.
主要成果:
- 低sMg与糖尿病和类固醇使用有关.
- 高sMg与脂质不良症,功能障碍和重症监护室停留有关.
- 低和高的sMg水平与增加的全因死亡率相关 (p < 0.001).
- 在调整后,低sMg独立预测死亡率增加 (HR = 1.57,p < 0.001).
结论:
- 低血清水平和高血清水平都与COVID-19患者的死亡率增加有关.
- 低血清独立预测死亡率,即使考虑到功能障碍和疾病严重程度.
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