参与葡萄糖恒温和体重控制的墨西哥植物:系统性审查
Montserrat Torres-Vanda1, Ruth Gutiérrez-Aguilar1,2
1Laboratorio de Investigación en Enfermedades Metabólicas: Obesidad y Diabetes, Hospital Infantil de México "Federico Gómez", Mexico City 06720, Mexico.
Nutrients
|July 11, 2023
概括
墨西哥的药用植物在治疗2型糖尿病和肥胖方面表现有前途. 鉴定出了五种特定的植物,它们具有调节血糖和胰岛素分泌的潜力,为代谢健康提供了天然替代品.
科学领域:
- 民族植物学 民族植物学
- 药理学 药理学是指药理学的学科.
- 代谢健康 代谢健康
背景情况:
- 肥胖和2型糖尿病是全球重要的健康问题,其流行率正在上升.
- 目前的治疗方法昂贵,引发了人们对传统医学等替代疗法的兴趣.
- 药用植物在传统实践中广泛用于治疗各种疾病,包括代谢障碍.
研究的目的:
- 为了确定传统上用于2型糖尿病和体重管理的墨西哥药用植物.
- 寻找可能积极影响胰岛素分泌和控制体重的植物.
主要方法:
- 在PubMed,Google Scholar和Scopus中进行了一项文献搜索,寻找墨西哥植物.
- 纳入标准集中在显示显著降低血糖或增加胰岛素分泌量的植物上.
- 审查了研究,以确定具有低血糖和体重控制作用的植物.
主要成果:
- 最初确定了306种墨西哥植物具有低血糖作用.
- 根据胰岛素分泌量增加的证据,选择了五种植物:Momordica charantia,Cucurbita ficifolia,Coriandrum sativum,Persea americana和Bidens pilosa.
- 这些植物的提取物显示出改善葡萄糖耐受性,胰岛素敏感性和胰腺β细胞功能的潜力.
结论:
- 需要进一步的体内和体外研究来阐明作用机制.
- 了解这些机制对于开发2型糖尿病和肥胖的植物性治疗至关重要.
- 这些药用植物代表了未来治疗发展的有希望的领域.
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