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一项基于日本40个功能主张 (FFC) 的食品系统评价的跨部门研究:使用AMSTAR 2进行质量评估
Hiroharu Kamioka1, Hideki Origasa2, Kiichiro Tsutani3
1Faculty of Regional Environment Science, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan.
Nutrients
|July 11, 2023
概括
支持功能声明的日本食品的系统审查的方法质量非常差. 大多数审查在协议注册,搜索策略和偏见风险评估方面存在严重缺陷.
科学领域:
- 食品科学 食品科学 食品科学
- 关于健康索赔的规定
- 基于证据的医学基于证据的医学.
背景情况:
- 日本在2015年引入了功能宣称食品 (FFC),以增加产品的可用性.
- FFC需要科学证据,主要来自系统性审查 (SRs),以支持健康主张.
- 用于FFC使用的SR的方法质量尚未先前评估.
研究的目的:
- 评估日本FFC提交的SR的方法质量.
- 确定支持FFC产品的SR中常见的缺陷.
主要方法:
- 从2022年4月到10月进行了数据库搜索.
- 评估方法标准工具2 (AMSTAR 2) 检查清单被用于评估SR质量.
- 40个SR被随机抽取用于分析.
主要成果:
- 95%的SR被评为"非常低"质量 (N=38),5%的SR被评为"低"质量 (N=2).
- 平均AMSTAR 2评分为51.1%,表明存在重大质量问题.
- 常见的缺陷包括缺乏协议注册,不足的搜索策略和不充分的偏见风险评估.
结论:
- 在日本,支持FFC的SR的方法质量非常差.
- 在协议注册,全面的文献搜索和偏见风险评估方面发现了严重的缺陷.
- 这些发现表明,需要改善FFC产品的证据生成标准.
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