未经治疗的骨质疏松症和高FRAX作为牙脱落的风险因素:一项为期5年的前性研究
Daniela Cia Penoni1,2, Sandra Regina Torres3, Matheus L Oliveira4
1Division of Dentistry, Brazilian Navy, Hospital Naval de Brasília, SEPS Q 711/911, Federal District, Asa Sul, Brasília, DF, 70390-115, Brazil. ciapenoni@gmail.com.
Journal of bone and mineral metabolism
|July 11, 2023
概括
未经治疗的骨质疏松症和更高的骨折风险 (FRAX) 在老年妇女中显著增加了牙损失. 至少三年进行适当的骨质疏松症管理可以减轻这种风险,强调了骨和牙周综合护理的重要性.
科学领域:
- 老年学是指老年学的学科.
- 牙周病学 牙周病学
- 骨质疏松症研究研究
背景情况:
- 骨健康状况下降,包括骨质疏松症和骨折风险增加,与恶化的牙周病和牙脱落有关.
- 这项前性研究调查了老年妇女的系统性骨状况和因牙周病而导致的牙脱落之间的关联.
研究的目的:
- 为了确定系统性骨状况是否是65岁及以上妇女牙周病引起的牙损失的危险因素.
- 评估骨质疏松症和骨折风险概率对五年期间牙周健康结果的影响.
主要方法:
- 这是一项为期5年的前性研究,涉及74名65岁以上的妇女接受牙周检查.
- 基线评估包括骨质疏松症状况和骨折风险概率 (FRAX). 参与者根据骨矿物质密度 (BMD) 和骨质疏松症治疗持续时间分类.
- 主要结局是在5年后的随访中因牙周病而导致的牙损失,记录了牙周炎的分期/分级以及牙损失的原因.
主要成果:
- 没有治疗或短期治疗骨质疏松症的女性,与正常骨质疏松症或接受治疗3年以上 (RR=4.00) 的女性相比,患有牙周病的牙损失风险增加了四倍.
- 较高的FRAX得分与增加的牙损失有显著的关联 (RR=1.25).
- 牙损失的病史表明更糟糕的主要FRAX分数的可能性更高 (灵敏度=72.2%,特异性=72.2%).
结论:
- 未经治疗的骨质疏松症和升高的FRAX是老年妇女因牙周病而导致牙脱落的重要危险因素.
- 适当的骨质疏松症管理 (≥3年治疗) 或正常的骨髓质量与牙损失的风险没有增加有关.
- 骨健康和牙周护理的综合管理对于预防牙脱落至关重要.
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