年龄不是障碍:老年人的CAR-T疗法
Joseph E Maakaron1, Basem M William2
1University of Minnesota, Minneapolis, MN, USA.
Drugs & aging
|July 11, 2023
概括
化学抗原受体-T (CAR-T) 细胞疗法正在彻底改变癌症治疗. 本综述表明,CAR-T疗法可以安全地给老年人使用,特别是在扩散性大B细胞淋巴瘤中.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 血液学 血液学 血液学
背景情况:
- 化学抗原受体-T (CAR-T) 细胞疗法已经改变了血液恶性瘤治疗.
- 增加CAR-T产品的可用性和处方方便使其使用范围扩大.
- 卡特-T疗法具有显著的毒性,可能会限制在某些患者群体中的适用性.
结论:
- 在老年人中,CAR-T细胞疗法表现出有利的安全性.
- 这些发现支持CAR-T在患有血液性恶性瘤的老年患者中的更广泛应用.
- 进一步的研究可能会阐明老年人的特定风险-益处概况.
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