童年不良经历与美国年轻成年人感染人类乳头瘤病毒疫苗覆盖率之间的关联:一项跨部门研究
Shengruo Zhang1, Barbra A Richardson, John Lin1
1From the Departments of Epidemiology.
Sexually transmitted diseases
|July 11, 2023
概括
儿童不良经历 (ACE) 意外地与年轻成年人更高的人类乳头瘤病毒 (HPV) 疫苗接种率有关. 这表明,预防性卫生服务对有ACE病史的个人有潜在的益处.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 预防医学 预防医学
背景情况:
- 不良的童年经历 (ACE) 与负面的成年健康结果有关.
- 预防性卫生服务,如人类乳头瘤病毒 (HPV) 疫苗接种,可能会减轻ACE的影响.
- 了解ACE与疫苗接种的关联对于公共卫生干预至关重要.
研究的目的:
- 研究年轻成年人ACE和HPV疫苗接种覆盖率之间的关系.
- 为了确定特定类型的ACE是否会影响HPV疫苗接种的启动和完成.
- 探索与其他健康行为的二次关联.
主要方法:
- 来自2019-2020年行为风险因素监测系统的3415名年轻成年人 (18-29岁) 的分析.
- 包括各种ACE:情绪,身体,性虐待,家庭功能障碍,父母分居等.
- 用于计算疫苗接种关联的流行率 (PRs) 的日志双项回归模型.
主要成果:
- 一些ACE,包括情绪滥用和药物滥用,与HPV疫苗接种启动和完成有积极关联.
- 相反,ACE与流感疫苗接种和最近的例行检查有负面关联.
- ACE与艾滋病毒检测和艾滋病毒相关的风险行为有积极的关联.
结论:
- 在ACE和HPV疫苗接种覆盖率之间观察到意想不到的积极关联.
- 这些发现可能表明通过STI/HIV预防服务增加了对HPV疫苗接种的机会.
- 建议在青春期早期对ACE和及时接种HPV疫苗进行进一步的研究.
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