新血管与年龄相关的黄斑变性和糖尿病黄斑的治疗方法
1Senior retina partner and vice president, Carolina Eye Associates, PA, in Southern Pines, NC; adjunct assistant professor at Campbell University School of Medicine, Lillington, NC.
The American journal of managed care
|July 11, 2023
概括
神经血管与年龄相关的黄斑变性 (nAMD) 和糖尿病黄斑 (DME) 治疗因成本和频繁的注射而面临患者遵守的挑战. 新兴的策略和个性化护理旨在减少治疗负担并改善这些视网膜疾病的结果.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 医疗治疗 医疗治疗
背景情况:
- 神经血管与年龄相关的黄斑变性 (nAMD) 和糖尿病黄斑 (DME) 给患者带来了很大的疾病负担.
- 存在诊断和治疗的临床指南,以抗血管内皮生长因子 (VEGF) 治疗作为标准的护理.
- 目前的抗VEGF疗法虽然有效,但由于成本,频繁的内注射和诊所访问,对患者长期遵守药物提出了挑战.
研究的目的:
- 审查目前对nAMD和DME的治疗方法.
- 探索新兴的治疗方法和剂量策略,以减少患者的治疗负担.
- 强调视网膜专家在优化患者特异性治疗策略以改善临床结果方面的作用.
主要方法:
- 对nAMD和DME现有的临床指南的审查.
- 分析当前的药理疗法,包括抗VEGF药物.
- 讨论新出现的治疗方式和剂量策略.
- 重点是针对患者的,基于证据的治疗优化.
主要成果:
- 抗VEGF治疗是对nAMD和DME的既定治疗标准.
- 患者对当前治疗的遵守可能受到成本和注射频率等因素的限制.
- 新的治疗方法和战略剂量旨在提高患者的安全性并降低治疗负担.
结论:
- 优化nAMD和DME的管理需要解决患者合规障碍.
- 新兴疗法和个性化治疗计划有望改善患者的治疗结果.
- 视网膜专家对于将基于证据的策略与个体患者的需求量身定制至关重要,以获得更好的临床结果.
更多相关视频
06:48Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium
Published on: August 7, 2015
21.4K
07:04Electroporation-Based Genetic Modification of Primary Human Pigment Epithelial Cells Using the Sleeping Beauty Transposon System
Published on: February 4, 2021
2.1K
相关概念视频
Open Angle Glaucoma: Treatment
481
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
481
Angle Closure Glaucoma: Treatment
574
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
574
Diabetes: Management and Pharmacotherapy
319
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
319
Glaucoma: Overview
623
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
623
