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一个血管多臂多阶段试验,以预防大腿伤口手术部位感染:一个可行性调查

Matthew A Popplewell¹, Brenig L Gwilym², Ruth A Benson¹

¹Institute of Applied Health Research, University of Birmingham, Birmingham, UK.

International wound journal

|July 11, 2023

概括

动脉手术后手术部位感染 (SSI) 是常见的. 血管外科医生认为沟伤口SSI是一个主要问题,并支持三项预防性干预的随机对照试验 (RCT).

科学领域:

血管外科血管外科
预防传染病预防传染病
临床试验临床试验

背景情况:

手术部位感染 (SSI) 是动脉手术后的常见并发症,特别是涉及沟切口的动脉手术.
有限的证据表明,有效的干预措施可以预防关节伤口的SSI.
预防部伤口SSI对于患者的治疗结果和医疗保健成本至关重要.

研究的目的:

调查血管临床医生对当前实践的意见,并为一项随机对照试验 (RCT) 准备调查预防部伤口SSI的干预措施.
评估三个具体干预措施的可行性和外科医生接受度:浸的切口窗,二甲基化敷料和浸抗生素的原海绵.
为了衡量在血管外科社区内感知部伤口SSI的意义.

主要方法:

在大不列颠和爱尔兰血管学会2021年年度科学会议上,对参与者进行了一项调查.
该调查利用研究电子数据捕获 (REDCap) 平台收集对三个不同的SSI预防干预措施的回应.
75名咨询血管外科医生填写了问卷,提供了关于感知问题的数据,接受干预,以及RCT的临床设备.

主要成果:

绝大多数受访者 (97.3%) 认为关节伤口SSI是一个重大问题.
很高的百分比 (83.6%) 表示愿意使用调查的干预措施,93.3%表示临床设备随机患者.
关于偏离浸切口窗,一些人认为这是当前的护理标准,注意到了一些不情愿.

结论:

地面伤口SSI被认为是血管外科手术的一个主要挑战.
一个多中心RCT评估三种新的预防干预措施与标准护理相比,被血管外科医生认为是可以接受的.
这些发现支持对有效的部伤口SSI预防策略进行进一步研究的可行性.

关键词:

手术部位感染手术部位感染血管外科手术血管外科

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