患有COVID-19的重病老年人的结果:一个多中心的回顾性队列研究
Kiyan Heybati1, Eric K C Wong2,3,4, Jennifer Watt2,3,4
1Mayo Clinic Alix School of Medicine, Mayo Clinic, Rochester, MN, USA.
概括
由于COVID-19而入住重症监护室 (ICU) 的老年人面临长时间住院和高死亡率. 高龄和器官支持需要预测死亡,而女性的性别是保护性的.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 老年病的医生 老年病的医生
背景情况:
- 患有COVID-19的老年人经历了严重的并发症和死亡率.
- 相当数量的老年患者需要因严重的COVID-19而入住重症监护室 (ICU).
研究的目的:
- 描述ICU中COVID-19的老年人 (≥65岁) 的管理和结果.
- 在这个脆弱人群中确定住院死亡率的预测因素.
主要方法:
- 在2020年3月至2021年6月期间,对273名65岁以上的患者进行了回顾性队列研究,这些患者在多伦多重症监护室住院.
- 收集关于患者特征,ICU治疗和结果的数据.
- 多变量逻辑回归用于识别死亡率预测因素.
主要成果:
- 平均年龄为74岁,52%的患者在住院后幸存下来.
- 不幸存者比幸存者更老,而且与幸存者相比,女性的可能性更低.
- 较高的APACHE II分数,年龄增加和器官支持需求预测了住院死亡率;女性性别与较低的死亡率有关.
结论:
- 更年长的重症COVID-19患者长期在ICU/医院住院,死亡率高.
- 需要进行进一步的研究,以优化ICU入院决策,并评估这一人口群体的住院后结果.
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