住院老年患者的多病症和多药性:一个横截面研究
Yong Zhao1, Jianchun Wang2, Xiaojuan Zhu3
1Department of Geriatric Cardiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 JingWu Road, Jinan, 250021, Shandong, China.
BMC geriatrics
|July 11, 2023
概括
这项研究发现,多病症影响超过91%的住院老年人. 虽然多药 (5+类药物) 与发病率增加有关,但它也与该人口的死亡风险降低有关.
科学领域:
- 老年学是指老年学的学科.
- 临床药房 临床药房
- 流行病学 流行病学
背景情况:
- 全球人口正在老龄化,导致老年人多病症和多药症的患病率增加.
- 这些情况与不良健康结果和医疗保健支出增加有关.
- 住院的老年患者 (60岁以上) 是一个需要专注调查的弱势群体.
研究的目的:
- 在一大批住院老年患者中调查多病症和多药症的流行率和状况.
- 识别与多病症和多药性相关的因素.
- 检查这些疾病与全因死亡率之间的关系.
主要方法:
- 在2021年1月1日至12月31日期间,对46799名60岁以上的住院患者进行了回顾性横截面研究.
- 多病症定义为≥2种同时存在的疾病;多药性定义为≥5种口服药物.
- 使用斯皮尔曼等级相关性和后勤回归分析来评估关联并预测风险因素.
主要成果:
- 综合发病率为91.07%,随着年龄的增长而增加. 多种药物的流行率为56.32%.
- 高龄,多药,长期停留 (LOS) 和更高的药物成本与更多的疾病相关.
- 发病率数和LOS预测多药;年龄,发病率数和LOS预测全因死亡. 值得注意的是,多药与降低死亡率有关.
结论:
- 多发病率和住院时间 (LOS) 是多药性和住院老年人全因死亡率的潜在预测因素.
- 口服药物的数量与全因死亡风险呈反向关联.
- 适当的多药学可以为住院老年患者的临床结果带来好处.
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