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在人类组织中为无意义介导的mRNA衰变调节绘制基因变异

Bo Sun1, Liang Chen2

  • 1Department of Quantitative and Computational Biology, University of Southern California, 1050 Childs Way, Los Angeles, CA, 90089, USA.

Genome biology
|July 11, 2023
PubMed
概括

遗传变异影响人类组织中无意义介导的mRNA衰变 (NMD) 基因调节. 这些NMD定量特征位点 (NMD-QTLs) 是组织特异性的,特别是在大脑中,并且与疾病风险有关.

关键词:
衰变效率 衰变效率 衰变效率 衰变效率疾病SNP是疾病的SNP.标签: 标签: GTEx 标签: 美国遗传变体的遗传变体遗传基因组学的基因组学在 NMD-QTL 中.无稽之谈介导的mRNA衰变是没有意义的.转录后的监管 转录后的监管在RNA结合蛋白质中的RNA结合蛋白.这是一个小RNARNA.

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