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Updated: Jul 23, 2025

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
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Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

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使用循环离子移动和电子捕获解离的中下质量范围的同位素蛋白质的完全分离和测序

Francis Berthias1, Dale A Cooper-Shepherd2, Frederik H V Holck1

  • 1Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark.

Analytical chemistry
|July 12, 2023
PubMed
概括

这项研究引入了一种新的循环离子运动谱法,加上电子捕获解离 (cIM-MS/MS(ECD)) 来分离和测序异构的复杂混合物. 这种先进的技术成功地区分了非常相似的蛋白质形式,这对于理解它们的生物功能至关重要.

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