术后ICU要求与Fontan手术中的早期输出管的相关性
Keriann L Potter1, Marc E Richmond1, Andrew B Goldstone2
1Division of Pediatric Cardiology, NewYork-Presbyterian Morgan Stanley Children's Hospital, Columbia University Irving Medical Center, New York, NY, USA.
Cardiology in the young
|July 12, 2023
概括
在Fontan手术后的早期输出管 (EE) 减少了对血管活性-无热支持 (VIS) 的需求. 然而,现代队列中的晚期输出管 (LE) 患者需要更多的静脉注射液体 (IVF),这表明需要进一步研究的高风险组.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心脏外科手术 心脏外科手术
- 密集护理医学 密集护理医学
背景情况:
- 芬坦手术是一种复杂的手术,用于单心室先天性心脏缺陷.
- 优化术后护理,包括输出管的时间,对于患者的治疗结果至关重要.
- 了解早期输出管 (EE) 对重症监护室 (ICU) 支持的影响至关重要.
研究的目的:
- 调查早期输出管 (EE) 与Fontan手术后术后ICU支持程度之间的关联.
- 评估EE对静脉注射液 (IVF) 容量和血管活性-异位积 (VIS) 的影响.
主要方法:
- 对接受丰丹息治疗的患者 (2008-2018) 的回顾性分析.
- 对EE率的倡议前 (控制) 和倡议后 (现代) 队列的比较.
- 用ANOVA或克鲁斯卡尔-瓦利斯试验进行详细分析,分为早期 (EE) 和晚期 (LE) 的分层.
主要成果:
- 与对照组 (42.6%) 相比,现代队列中的EE率显著增加 (75.7%).
- 现代队列的VIS中位数较低,但总体IVF平均值较高.
- 现代队列中的晚期抽管 (LE) 患者表现出最高的VIS和试管婴儿需求,接受了67%以上的试管婴儿,并在24小时内获得更高的VIS中位数.
结论:
- 在Fontan手术后的早期输出管 (EE) 与手术后的血管活性-异位积分 (VIS) 降低有关.
- 现代队列中的晚期输出管 (LE) 患者代表了一个高危子组,需要更多的试管婴儿和潜在的密集监测.
- 对这种高风险的LE子组进行进一步调查是有必要的,以优化Fontan的患者护理.
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