N端盖的交换有助于热友性脂酶TrLipE的基质特异性和活性

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Updated: Jul 23, 2025

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Yakun Fang1,2, Fan Liu1,2, Yi Shi1,2

  • 1National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, Jiangnan University, Wuxi, Jiangsu, China.

Frontiers in microbiology
|July 12, 2023
PubMed
概括

这项研究通过交换其N端盖来改进其弱酶活性来设计热友性脂酶 (TrLipE). 特定突变显著提高了TrLipE在工业应用中的催化效率.

关键词:
约束的能量 约束的能量盖子交换 盖子交换分子动力学分子动力学基质特异性 基质特异性热友性脂酶是一种热友性脂酶.

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