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脊椎压缩骨折支架后的临床结果:随机试验的系统审查和元分析

Mathieu Squires¹, Jordan Howard Green¹, Rakesh Patel¹

¹Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.

Journal of spine surgery (Hong Kong)

|July 12, 2023

概括

脊椎压缩骨折的刚性支架可能会在短期内减轻疼痛,但不会带来长期益处. 软支架是一种可行的替代方案,因为在刚性和软支架的有效性之间没有发现显著差异.

科学领域:

整形外科整形外科整形外科
脊柱外科手术脊柱外科手术
老年医学老年医学

背景情况:

脊椎压缩骨折很普遍,导致严重的疼痛和功能障碍.
目前这些骨折的治疗策略缺乏最终的共识.
护是一种常见的干预措施,但它的有效性仍在争论中.

研究的目的:

进行随机对照试验 (RCT) 的元分析.
评估支架治疗对脊椎压缩骨折疼痛,功能和放射结果的影响.
为了比较刚性支架,软支架和没有支架.

主要方法:

在Embase,OVID MEDLINE和Cochrane图书馆进行了系统的文献搜索.
包括三项涉及447名患有胸部和腰部压缩骨折的成年患者的RCT.
使用随机效应模型评估疼痛,功能,生活质量,阿片类药物使用和囊性进展.

主要成果:

与没有支架相比,刚性支架在受伤后3-6个月显著降低了疼痛 (SMD =-1.32).
这种疼痛减轻在长期随访 (48周) 中减少.
在任何时间点在组之间都没有观察到功能,生活质量,阿片类药物使用或囊性进展的显著差异.

结论:

中等证据表明,刚性支架可以缓解脊椎压缩骨折的短期 (长达6个月) 疼痛.
护与不护之间在放射学参数,阿片类药物使用,功能或生活质量方面没有发现显著差异.
软支架似乎是刚性支架的适当替代品,因为没有注意到结果的显著差异.

关键词:

整形骨架的正确位置是什么?支架支架支架支架压缩压缩的压缩方式骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折.脊椎脊椎是指脊椎的脊椎.

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