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Updated: Jul 23, 2025

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
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2019年生物分子资源设施协会多实验室数据独立获取蛋白质组学研究

Joanna Kirkpatrick1,2, Paul M Stemmer3, Brian C Searle4,5

  • 1Leibniz Institute on Aging Fritz Lipmann Institute 07745Jena Germany.

Journal of biomolecular techniques : JBT
|July 12, 2023
PubMed
概括

蛋白质组学中的数据独立获取 (DIA) 显示出减少缺失值和增加数据深度的前景. 这项大型的实验室间研究为DIA方法的开发和评估提供了有价值的基准数据集.

关键词:
数据独立的获取采集.没有标签的量化量化.蛋白质组学 蛋白质组学入量化的量化.

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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