设计和SICK的内部验证. :一种新的诺米图,可以预测皮肤穿透性神经利息切除术后的感染和出血事件
Giorgio Mazzon1, Caterina Gregorio2, Jiehui Zhong3
1Department of Urology, Guangdong Key Laboratories, the first Affiliated Hospital of Guangzhou Medical University, Guangzhou, China - giorgio mazzon83@gmail.com.
Minerva urology and nephrology
|July 12, 2023
概括
这项研究引入了一种新的名图,用于预测皮肤透神经切除术 (PCNL) 后的传染性和出血性并发症. 该工具确定了关键的风险因素,以改善患者管理和结果.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 手术并发症 手术并发症
背景情况:
- 皮肤透神经切除术 (PCNL) 可能导致严重的出血和感染并发症.
- 目前用于预测PCNL并发症的诺姆图的可靠性值得争议.
- 提出了一种新型的诺米图,以提高对这些不良事件的预测能力.
研究的目的:
- 开发和验证一种新的诺米克图,用于预测PCNL后的传染病和出血并发症.
- 确定与早期术后并发症相关的术前风险因素.
- 为了帮助临床医生在PCNL的外科手术期间患者管理.
主要方法:
- 一项多中心前性研究,涉及接受标准或迷你PCNL的成年患者.
- 利用了之前一项随机对照试验 (RCT) 的数据.
- 分析了发烧,败血症休克,输血和血管栓塞的危险因素.
主要成果:
- 包括1980名患者;992人 (50.1%) 患有迷你PCNL,848人 (49.9%) 患有标准PCNL.
- 整体并发症率为11.7%,包括发烧 (8.9%),尿道塞普斯 (0.7%),输血 (1.2%) 和血管栓塞 (0.9%).
- 预测因素包括年龄,BMI,石块大小,血红蛋白,糖尿病,eGFR,高血压,以前的PCNL和水. 该模型实现了0.73.3的AUC.
结论:
- 开发了一种新型的诺米图,用于预测PCNL后感染和出血.
- 诺米图表在识别有风险的患者方面表现出很好的准确性.
- 这种工具可以帮助临床医生在PCNL患者的术后评估和管理.
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