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在入院时,高血清中白素-6度可预测儿科创伤患者的疾病严重程度

Yingge Ma¹, Yujun Wang², Yanna Yao³

¹Department of Emergency, Xi'an Children's Hospital (The Affiliated Children's Hospital of Xi'an Jiaotong University), No. 69, Xi JuYuan Lanc, Lian Hu District, Shaanxi, 86-710003, People's Republic of China.

European journal of trauma and emergency surgery : official publication of the European Trauma Society

|July 12, 2023

概括

血清中介质素-6 (IL-6) 水平与儿科创伤严重程度有显著的相关性. 升高的IL-6表明更严重的伤害,作为儿童疾病活动的关键预测因素.

科学领域:

儿科急救医学儿科急救医学
创伤外科手术创伤外科
临床免疫学临床免疫学

背景情况:

创伤是全球儿童死亡的主要原因之一.
监测儿科创伤患者的炎症反应对于评估受伤严重程度至关重要.
血清干白素-6 (IL-6) 是潜在的炎症状态的生物标志物.

研究的目的:

评估血清IL-6水平对儿科患者创伤严重程度的预测值.
评估儿科创伤中IL-6水平与疾病活性之间的临床关联.

主要方法:

在17个月内对106名儿科创伤患者进行前性研究.
测量了血清IL-6水平,并与儿科创伤评分 (PTS) 相对应.
包括Spearman测试在内的统计分析被用来确定相关性.

主要成果:

在71.70%的患者中观察到IL-6水平升高.
在IL-6水平和PTS之间发现了显著的负相关性 (r_s = -0.757,p <0.001).
IL-6与各种临床标记物相关,包括肝酶,白细胞,乳酸,IL-10,hs-CRP,葡萄糖,纤维素和pH.

结论:

血清IL-6水平随着儿科创伤严重程度的升级而显著增加.
儿科创伤患者的IL-6作为预测疾病严重程度和活动的有价值指标.

关键词:

介乐金-6 介乐金-6 是一种儿科儿科儿科儿科创伤得分儿科创伤得分创伤是一个创伤.

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