PROMIS的珍珠和陷在骨科手术中具有临床意义的结果
Ron Gilat1,2, Ilan Y Mitchnik3,4, Sumit Patel5
1Department of Orthopaedic Surgery, Shamir Medical Center and Tel Aviv University, Tel Aviv, Israel. ron.gilat@gmail.com.
Archives of orthopaedic and trauma surgery
|July 12, 2023
概括
患者报告结果测量信息系统 (PROMIS) 越来越多地用于骨科研究中的临床显著结果,特别是用于下肢手术. 基于的最小临床重要差异 (MCID) 提供了比基于分布的更保守的措施.
科学领域:
- 整形外科的研究.
- 测量健康结果的测量结果
- 患者报告的结果
背景情况:
- 患者报告结果测量信息系统 (PROMIS) 提供了一种标准化的方法来测量患者的结果.
- PROMIS利用项目响应理论和计算机自适应测试来获得可概括的结果.
- 评估PROMIS在骨科研究中的使用对于临床显著结果 (CSO) 是至关重要的.
研究的目的:
- 评估PROMIS在骨科研究中测量社会公益组织的应用.
- 提供关于PROMIS在这个领域的优势和局限性的见解.
主要方法:
- 在多个数据库中对2016-2022年的出版物进行了系统审查.
- 通过使用纽卡斯尔-太华尺度 (NOS) 和问卷符合性来评估研究的偏见.
- 一项元分析比较了低偏差研究中的基于分布和基于的临床重要的最小差异 (MCID).
主要成果:
- 审查了54篇出版物,主要侧重于下肢手术.
- 疼痛功能 (PF),疼痛干扰 (PI) 和抑郁症 (D) 是最常被评估的PROMIS领域.
- 据发现,基于的MCID大于基于分布的MCID,这表明了更为保守的措施.
结论:
- 普罗米斯 (PROMIS) 的民间社会组织在骨科研究中越来越受欢迎,特别是在下肢手术方面.
- 使用基于的MCID和报告最小可检测变化 (MDC) 可以提高研究的稳定性.
- 研究人员在使用PROMIS进行CSO评估时应注意具体考虑因素.
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