建立一个新的预测模型来预测上尿路结石的复发
Kaiguo Xia1,2,3, Yuexian Xu1,2,3, Qiao Qi1,2,3
1Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
International urology and nephrology
|July 12, 2023
概括
这项研究开发了一种名字图来预测上部泌尿道石头的复发. 该模型识别了诸如多重或双边结石和肌素升高等危险因素,有助于术后患者管理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗信息学 医疗信息学
背景情况:
- 上部尿路结石对健康构成重大挑战.
- 预测石头复发对于有效的患者管理和预防并发症至关重要.
研究的目的:
- 开发和验证用于评估上尿路结石复发风险的诺米克图.
- 确定与石头复发相关的关键临床和生化因素.
主要方法:
- 对657名患上尿路结石的患者进行了回顾性分析.
- 包括LASSO和后勤回归在内的统计分析,以确定重要的预测因素.
- 使用R软件开发一个名ogram,并通过ROC曲线分析进行评估.
主要成果:
- 多重结石,双边结石,结石和尿管结石被确定为复发的高风险因素.
- 复发风险与肌素,尿液pH和Apolipoprotein B (Apo B) 有正相关,与血清有负相关.
- 该名录显示灵敏度为73.08%,特异性为61.25%.
结论:
- 开发的诺米图有效地预测了上部泌尿道石的复发风险.
- 这种工具对于术后患者来说尤其有益,以减轻复发的可能性.
- 与单个变量相比,名图提供了更高的诊断价值.
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