主动监控是否过于积极?
James T Kearns1, Brian T Helfand2
1Division of Urology, NorthShore University HealthSystem, 2180 Pfingsten Rd., Suite 3000, Glenview, Evanston, IL, 60026, USA. jkearns@northshore.org.
Current urology reports
|July 12, 2023
概括
目前的前列腺癌积极监测协议可能涉及过度测试. 虽然MRI和生物标志物有助于风险分层,但定期活检仍然对安全至关重要,因为遗漏它们尚未被证明是可行的.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医学诊断 医学诊断 医学诊断
背景情况:
- 积极监测是管理低风险前列腺癌的常见策略.
- 协议通常包括频繁的监测,如PSA测试,诊所访问,MRI和活检.
研究的目的:
- 评估目前的前列腺癌活跃监测协议是否导致过度测试.
- 评估串行监控组件的必要性和实用性.
主要方法:
- 对多参数MRI,血清生物标志物和连续前列腺活检的最新研究进行审查.
- 分析这些工具在主动监控中的预测价值.
主要成果:
- 多参数MRI和血清生物标志物显示出风险分层的前景.
- 没有证据支持在积极监测中安全地省略定期前列腺活检.
- 额外的MRI或生物标志物并不能持续改善更高程度疾病的预测.
结论:
- 目前的积极监测协议可能对一些患者来说过于密集.
- 定期的前列腺活检仍然是积极监测安全的关键组成部分.
- 需要进一步的研究,以优化监测策略,而不会影响患者的安全.
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