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Updated: Jul 23, 2025

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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通过利用外部总结数据来改进疾病亚型异质性的模型

Sheng Fu1, Mark P Purdue1, Han Zhang1

  • 1Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America.

PLoS computational biology
|July 12, 2023
PubMed
概括

PolyGIM集成了来自多项研究的总结数据,以评估疾病亚型异质性. 这种方法在没有个人数据的情况下有效评估风险影响,有助于理解诸如非霍奇金淋巴瘤 (NHL) 等复杂疾病.

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