基底质在天生的和学习的行为序列中的作用
Natalia Favila1, Kevin Gurney2, Paul G Overton2
1German Center for Neurodegenerative Diseases, 53127 Bonn, Germany.
Reviews in the neurosciences
|July 12, 2023
概括
行为分类,即将行为组织成自动单元,是基本的. 基底,特别是条纹体,是通过控制中央模式生成器来对行为进行测序的关键.
科学领域:
- 神经科学是一个神经科学.
- 行为生物学 行为生物学
- 发动机控制器的控制器
背景情况:
- 为了实现自动性,将行动组织成连贯的单元 (块化) 是必不可少的.
- 基底质参与了动作选择和序列编码.
- 中央模式生成器 (CPG) 控制着先天的行为,脑干和脊柱的CPG是由像基底等更高的结构调节的.
研究的目的:
- 阐明基底质在行为块和动作序列编码中的作用.
- 了解条纹体如何为有序执行行为做出贡献.
- 探索条体在学习过程中作为更高阶模式生成器的潜力.
主要方法:
- 对脊椎动物的基底腺功能现有证据的审查.
- 对天生的和学习的行为序列 (例如,理,鸟声,操作条件) 的研究分析.
- 检查纹状体在选择和协调CPG中所扮演的角色.
主要成果:
- 基底,特别是条形,对于将简单的行为连接成复杂的行为块至关重要.
- 状体似乎通过选择适当的CPG和抑制其他物质来调节进入运动系统的途径.
- 状神经可以促进状体在学习过程中采用更高阶的模式生成函数.
结论:
- 基底腺是通过调节CPG将行动组织成顺序,自动行为的中心.
- 条形体在选择和订购运动程序方面发挥着关键作用,使复杂的行为序列成为可能.
- 纹状体的学习诱导的可塑性表明它可以充当动态模式生成器,适应越来越复杂的行为.
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