重复参加乳腺癌查对存活率的有益影响
Stephen W Duffy1, Amy Ming-Fang Yen2, Laszlo Tabar3
1Centre for Prevention, Detection and Diagnosis, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Journal of medical screening
|July 12, 2023
概括
定期参加乳房扫描查显著改善了乳腺癌的生存率. 与不参加任何检查相比,参加五次检查可将死于乳腺癌的风险降低约三倍.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 放射学 放射学是一门学科.
背景情况:
- 已经证明,乳房扫描查可以降低乳腺癌死亡率.
- 参与重复查对个体病例存活率的影响需要进一步估计.
研究的目的:
- 估计重复参加乳房扫描查对乳腺癌病例生存率的影响.
- 量化所参加的查次数与生存结果之间的关联.
主要方法:
- 对1992年至2016年期间被诊断患有乳腺癌的37079名妇女的发病率和生存率数据的分析.
- 估计与参与诊断前最多五次查的生存相关性.
- 使用比例危险回归来评估查频率对存活率的影响.
主要成果:
- 观察到一种剂量-反应关系:更高的查参与与更好的生存率相关.
- 参加所有五次查的女性,乳腺癌死亡率的危险比为0.28 (95% CI 0.25-0.33).
- 经过自我选择调整后,参加五次查后,患乳腺癌的死亡风险降低了大约三倍 (HR 0.34,95% CI 0.26-0.43).
结论:
- 定期参加乳房扫描查显著提高了被诊断为乳腺癌的妇女的生存率.
- 这些发现强调了持续的查遵守对于改善个体预后的重要性.
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