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Updated: Jul 23, 2025

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
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双链断裂修复中的顶端PIKK的结构和功能

Jingfei Xu1, Noah Bradley1, Yuan He1

  • 1Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.

Current opinion in structural biology
|July 12, 2023
PubMed
概括

酸丁醇3'激酶 (PI3K) 相关激酶 (PIKKs) 家族,包括DNA-PKcs,ATM和ATR,对于DNA修复至关重要. 这篇评论详细介绍了它们在DNA双链断裂修复途径中的最新结构和作用.

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