毒素A型对外围面部的功能,同运动和生活质量的影响
U Díaz-Aristizabal1, M Valdés-Vilches1, T R Fernández-Ferreras1
1Servicio de Rehabilitación y Medicina Física, Xarxa Sanitària i Social Santa Tecla, Tarragona, Spain.
Neurologia
|July 12, 2023
概括
毒素A (BTX-A) 注射改善了面部肌肉功能和生活质量,同时减少了患有外周面的患者的突触. 这种治疗对PFP恢复具有显著的益处.
科学领域:
- 神经学 神经学
- 眼科医生 眼科 眼科
- 整形外科 整形外科 整形外科
背景情况:
- 周围面部 (PFP) 的后果可能导致显著的功能和美学障碍.
- 面部肌肉不自发的运动 - - 联动运动 (synkinesis) 通常会使PFP恢复复杂化.
- 目前的治疗方法旨在改善面部对称性和功能,但管理后果的选择仍然有限.
研究的目的:
- 评估毒素A (BTX-A) 透在患有外围面部 (PFP) 后续症状的患者中的疗效.
- 评估BTX-A对面部肌肉功能,突触和患者报告的生活质量的影响.
主要方法:
- 这是一项前性研究,涉及20名患有PFP连续病例的患者,他们之前接受了神经肌肉再培训.
- 经过BTX-A (博托克斯或Xeomin) 透剂的使用.
- 在治疗前和治疗后4周使用桑尼布鲁克面部分级系统 (SFGS),面部临床评估问卷 (Facial Clinimetric Evaluation, FaCE) 和同运动评估问卷 (Synkinesis Assessment, SAQ) 进行了临床评估.
主要成果:
- 在SFGS平均得分 (64.8至69.9,P=.004) 中显著改善.
- 平均总FaCE分数 (52.42至64.5,P<.001) 和社会功能分级 (61.15至78.44,P<.001) 显著增加.
- 平均SAQ得分显著降低,表明突触酶降低 (46.22至37.55,P=.001).
结论:
- 透BTX-A是一种有效的治疗方法,用于改善PFP后续的面部肌肉功能.
- BTX-A可以改善患有PFP长期影响的患者的生活质量.
- BTX-A在降低PFP常见且具有挑战性的并发症协中发挥着重要作用.
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