从青春期到青春期大麻使用的变化及其与妊娠期酒精和大麻暴露的关系
Lidush Goldschmidt1, Gale A Richardson2, Nancy L Day2
1Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Neurotoxicology and teratology
|July 12, 2023
概括
产前酒精和大麻暴露显著影响青少年大麻使用过渡到年轻成人. 这些暴露,与同行影响和行为一起,预测长期物质使用模式.
科学领域:
- 发展心理学 发展心理学
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 有限的研究存在于影响大麻使用从青春期到年轻成年期过渡的因素.
- 青少年使用大麻的模式是复杂的,受到各种发展和环境因素的影响.
研究的目的:
- 为了检查产前酒精和大麻暴露,以及青少年的风险和保护因素,如何预测大麻使用轨迹从16岁到22岁.
- 在这个关键的发育时期,区分戒断,持续和停止使用大麻.
主要方法:
- 来自"孕产妇健康实践和儿童发展项目" (产前至22年随访) 的纵向数据.
- 用于识别大麻使用过渡的预测因素的歧视性分析.
- 风险因素包括产前物质暴露,16岁人口统计,行为和家庭环境.
主要成果:
- 确定了四个大麻使用过渡组:非使用者,停止/减少,继续/增加和16岁后开始使用.
- 关键的区分因素包括同龄人的大麻使用,犯罪,照顾者的财务压力,产前酒精和大麻暴露以及种族.
- 产前暴露是显著的预测因素,即使控制其他因素.
结论:
- 产前酒精和大麻暴露与大麻使用过渡到年轻成年有显著的关联.
- 孕期大麻暴露与早期开始/增加使用有关;酒精暴露与晚期开始有关.
- 研究结果强调了产前物质暴露对物质使用行为的持久影响.
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