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PC4介导的Ku复合PARylation促进了依赖NHEJ的DNA损伤修复

Qimei Pan1, Peng Luo1, Chunmeng Shi1

  • 1State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Rocket Force Medicine, Third Military Medical University (Army Medical University), Chongqing, China.

The Journal of biological chemistry
|July 12, 2023
PubMed
概括

人体正辅因子4 (PC4) 增强了DNA修复,导致肝细胞癌 (HCC) 的放射电阻. 向PC4可能会改善HCC患者的放射疗法的有效性.

关键词:
修复DNA损伤的修复在这里,你会看到K.K.K.PARP1 的第一部分这是一种PARylation.肝细胞癌是肝细胞癌.不同类的末端连接.积极的辅因子4 4

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