在接种COVID-19疫苗后,自我报告的月经变化的患病率和危险因素:丹麦队列研究
C Bisgaard Jensen1, B Hammer Bech1, S Nygaard Hansen1
1Department of Public Health, Aarhus University, Aarhus, Denmark.
Human reproduction (Oxford, England)
|July 12, 2023
概括
30%的妇女在接种COVID-19疫苗后报告了月经变化. 压力,疫苗担忧,严重的COVID-19和即时症状与这些变化有关,突出了潜在的风险因素.
科学领域:
- 生殖健康 生殖健康
- 疫苗学 疫苗学 疫苗学
- 流行病学 流行病学
背景情况:
- 有限的研究存在于COVID-19疫苗接种后月经变化的危险因素.
- 一些研究表明,在接种疫苗后,有暂时的,轻微的月经周期变化.
研究的目的:
- 为了识别与在2019年新冠肺炎 (COVID-19) 疫苗接种后报告月经变化相关的特征.
- 研究针对COVID-19接种疫苗的妇女月经变化的潜在风险因素.
主要方法:
- 一项基于人口的丹麦队列研究 (BiCoVac) 涉及13,648名16-65岁的月经妇女.
- 疫苗接种前收集的关于潜在风险因素 (生物,生理,心理) 的自我报告数据.
- 后勤回归分析以确定风险因素与疫苗接种后自我报告的月经变化之间的关联.
主要成果:
- 30%的妇女在接种COVID-19疫苗后报告了月经变化.
- 报告月经变化的可能性增加与即时疫苗症状,之前的严重COVID-19,高压力和疫苗接种前的疫苗担忧有关.
- 在使用荷尔蒙避孕药的周期正常的女性中观察到更低的几率.
结论:
- 一些因素,包括压力,疫苗问题和之前的COVID-19感染,与报道疫苗接种后的月经变化有关.
- 需要进一步的研究来确定这些自我报告的变化的因果关系和临床意义.
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