在自闭症成年人之间的差异中发现相似之处:两个复制的子组
Tulsi A Radhoe1, Joost A Agelink van Rentergem2, Carolien Torenvliet2
1Brain & Cognition, Department of Psychology, Dutch Autism & ADHD Research Center (d'Arc), University of Amsterdam, Nieuwe Achtergracht 129-B, 1018 WS, Amsterdam, The Netherlands. t.a.radhoe@uva.nl.
Journal of autism and developmental disorders
|July 12, 2023
概括
具有平均至高智能的自闭症成年人可以分为子组. 一个子组遇到更多的困难,可能会受益于专门的支持和护理.
科学领域:
- 神经发育障碍 神经发育障碍
- 成年自闭症研究研究
- 自闭症中的异质性
背景情况:
- 自闭症谱系障碍 (ASD) 是高度异质的,给个性化支持和预后带来了挑战.
- 在自闭症成年人中识别不同的子组可以完善理解和帮助有针对性的干预.
- 之前的研究还没有完全阐明自闭症成年人中特定的子组,他们对支持需求的智力平均至高.
研究的目的:
- 识别和描述自闭症成年人中具有平均至高智能的子组.
- 确定特定子组是否需要量身定制的支持和专业护理.
- 评估已确定的子组的外部有效性和特异性.
主要方法:
- 社区检测分析用于识别自闭症和非自闭症成年人的原始和复制样本中的子组.
- 数据包括14个与衰老,人口统计,心理因素和生活方式相关的问卷变量.
- 外部有效性是通过认知和心理困难以及生活质量 (QoL) 的措施来评估的. 通过包括患有注意力缺陷/多动症障碍 (ADHD) 的成年人来测试特异性.
主要成果:
- 自闭症和非自闭症的比较组形成了不同的子组.
- 在自闭症成年人中确定了三个子组,其中两个正在复制.
- 一个复制的子组表现出更高的脆弱性,报告了更多的认知/心理困难和较低的 QoL. 包括ADHD成年人并没有改变这些发现.
结论:
- 具有平均至高智能的自闭症成年人不是一个单一的群体,可以分为不同的子组.
- 一个特定的自闭症成年人子组似乎更容易受到伤害,需要有针对性的支持和专业护理.
- 需要进一步的研究来验证这些发现,并为确定的子组开发基于证据的干预措施.
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