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Updated: Jul 23, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
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结核病的遗传学:从单源性疾病和与疾病相关的变异中获得机械学的见解

Carola G Vinuesa1,2,3, Nan Shen4,5,6, Thuvaraka Ware7,8

  • 1The Francis Crick Institute, London, UK. carola.vinuesa@crick.ac.uk.

Nature reviews. Nephrology
|July 12, 2023
PubMed
概括

遗传因素显著影响系统性自身免疫,特别是系统性红斑狼 (SLE). 来自全基因组关联研究 (GWAS) 和测序的洞察力揭示了核酸感应和与年龄相关的B细胞 (ABCs) 如何驱动疾病发病.

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