描述实施试验和遵守专家建议的结果:系统审查
Pierre Nizet1,2, Adrien Evin3, Emma Brociero4
1Nantes Université, CHU Nantes, 44000, Pharmacie, France. pierre.nizet@chu-nantes.fr.
BMC geriatrics
|July 12, 2023
概括
本综述检查了描述抑郁症的研究,发现大多数关注药物和临床结果. 未来的研究应该优先考虑实施和临床结果,以便更广泛地采用减压实践.
科学领域:
- 药理学 药理学是指药理学的学科.
- 老年病的医生 老年病的医生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 降低处方的目的是通过停止不必要的药物来减少多药.
- 美国抑郁症研究网络 (USDeN) 发布了2022年测量抑郁症结果的建议.
- 本系统性审查评估了对USDeN建议进行干预试验的结果类别.
研究的目的:
- 为了确定在描述干预试验中使用的结果类别.
- 将已识别的结果类别与USDeN建议进行比较.
主要方法:
- 2012年1月至2022年1月期间发表的随机对照试验 (RCT) 的系统审查.
- 在 MEDLINE,Embase,PsychInfo 和 Cochrane 图书馆进行的搜索.
- 结果分为药物,临床,系统和实施类型.
主要成果:
- 包括36个RCT,主要集中在养老院的老年人身上.
- 报告中最常见的是药物治疗结果 (31项研究),其次是临床 (25项),系统 (18) 和实施结果 (7).
- 很少有研究报告了所有四种结果类型;只有3个报告了所有四种结果类型,10个报告了三个结果类型.
结论:
- 描述性研究越来越多地实施,但结果报告需要标准化.
- 优先考虑临床结果和制定具体的实施结果对于大规模采用至关重要.
- 这些发现为设计未来的真实世界抑郁症描述研究提供了洞察力.
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