在患有酒精使用障碍的退伍军人中,方法避免训练与Sham相比:随机对照试验的随机对照试验协议
M M Caudle1, R Klaming2,3, C Fong1
1San Diego Joint Doctoral Program in Clinical Psychology, San Diego State University, University of California, 6363 Alvarado Court, Suite 103, San Diego, CA, 92120, USA.
BMC psychiatry
|July 12, 2023
概括
近距离避开训练 (AAT) 正在研究作为一种计算机交付的疗法,以帮助退伍军人患有酒精使用障碍 (AUD) 和其他精神疾病. 这项试验旨在调查AAT是否会在加入标准门诊护理时改善康复结果.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 行为科学 行为科学
背景情况:
- 酒精使用障碍 (AUD) 经常与退伍军人的其他精神疾病同时发生.
- 靠近回避训练 (AAT) 是一种计算机交付的认知偏差修改,通过准隐性方法偏差来治疗AUD,显示出有前途.
- 作为AUD的辅助治疗,AAT在患有并发性精神疾病的退伍军人中的有效性需要进一步调查.
研究的目的:
- 评估AAT作为AUD的辅助治疗在接受标准门诊护理的退伍军人的有效性.
- 评估AAT对AUD恢复结果的影响,包括饮酒和酒精消费的功能后果.
- 使用fMRI检查AAT对酒精方法偏差和神经反应的行为指标的影响.
主要方法:
- 一个双盲随机对照试验,涉及136名退伍军人患有AUD和并发性精神疾病.
- 参与者将随机分配到接受6周的AAT或Sham条件,以及通常的护理.
- 评估将在基线,6周,3个月和6个月进行,其中一个子组接受fMRI.
主要成果:
- 这项研究代表了AAT作为AUD的辅助疗法的第一个随机对照试验,用于患有并发性精神疾病的退伍军人.
- 行为和神经成像数据将阐明AAT对酒精线索的方法偏差修改的程度.
- 结果将告知AAT作为AUD的低成本辅助治疗选择的潜力.
结论:
- AAT可能会为患有AUD和同时出现的精神疾病的退伍军人提供一种新的计算机交付干预措施.
- 这项研究旨在提供关于AAT在改善AUD恢复方面的有效性强有力的证据.
- 成功的结果可以将AAT确立为一种有价值,可访问的治疗模式.
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