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Updated: Jul 23, 2025

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
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儿童急性淋巴细胞白血病中的PI3K/AKT通路相关的微RNA变异

Yao Xue1,2, Xiaoyan Sun1,2, Jinyu Fu1,2

  • 1Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, China.

Pediatric blood & cancer
|July 12, 2023
PubMed
概括

与PI3K/Akt路径相关的微RNA (miRNA) 的遗传变异可能会影响儿童急性淋巴细胞白血病 (ALL) 风险. 这种miR-149 rs2292832变体表现出一种保护作用,并抑制了ALL细胞的增殖,这表明它在ALL的发病过程中发挥了作用.

关键词:
通过PI3K/AKT路径.急性淋巴细胞白血病急性淋巴细胞白血病这就是miRNAs.单个核酸的多态性.

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